An active researcher, Dr. Lapping-Carr and her colleagues developed the Chicago Sickle Cell Research Group. As part of this group, she has established an extensive database of samples from patients with sickle cell anemia at different key points during the disease. Her goal is to understand the variation in lung pathology across people with sickle cell disease in order to provide personalized care to those at higher risk and develop novel therapies.
Plasma Levels of MicroRNA Let-7c-5p May Predict Risk of Acute Chest Syndrome in Patients with Sickle Cell Disease.
Plasma Levels of MicroRNA Let-7c-5p May Predict Risk of Acute Chest Syndrome in Patients with Sickle Cell Disease. Int J Mol Sci. 2025 Apr 18; 26(8).
PMID: 40332489
Triaging Acute Chest Syndrome Clinical Decision-Making Using Bedside SaO2/FiO2 Ratio.
Triaging Acute Chest Syndrome Clinical Decision-Making Using Bedside SaO2/FiO2 Ratio. Blood Adv. 2025 Apr 03.
PMID: 40179390
Food insecurity and quality of life in patients with sickle cell disease.
Food insecurity and quality of life in patients with sickle cell disease. Pediatr Blood Cancer. 2024 Jul; 71(7):e31045.
PMID: 38687256
Sickle cell trait and multisystem trauma: an unaddressed urgent knowledge gap.
Sickle cell trait and multisystem trauma: an unaddressed urgent knowledge gap. Trauma Surg Acute Care Open. 2022; 7(1):e000955.
PMID: 35719190
Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease.
Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease. J Clin Med. 2022 Feb 03; 11(3).
PMID: 35160266
Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells".
Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells". Pediatr Res. 2021 03; 89(4):1036.
PMID: 33790407
Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome.
Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome. Int J Mol Sci. 2020 Nov 24; 21(23).
PMID: 33255173
Circulating Extracellular Vesicles and Endothelial Damage in Sickle Cell Disease.
Circulating Extracellular Vesicles and Endothelial Damage in Sickle Cell Disease. Front Physiol. 2020; 11:1063.
PMID: 33013455
Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells.
Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells. Pediatr Res. 2021 03; 89(4):776-784.
PMID: 32454519
Exosomes contribute to endothelial integrity and acute chest syndrome risk: Preliminary findings.
Exosomes contribute to endothelial integrity and acute chest syndrome risk: Preliminary findings. Pediatr Pulmonol. 2017 Nov; 52(11):1478-1485.
PMID: 28486752