Professor of Pediatrics
Section of Hematology/Oncology and Stem Cell Transplantation
University of Chicago
AB - Biological Sciences
UCSD
PHD - Physiology and Pharmacology
UCSD
MD - Medicine
Children's Hospital
Boston
Internship and Residency - Pediatrics
Children's Hospital and Dana Farber Cancer Center
Boston
Fellowship - Pediatric Hematology/Oncology
Editorial: Ion channels, pumps, and transporters in lens physiology and disease.
Editorial: Ion channels, pumps, and transporters in lens physiology and disease. Front Physiol. 2022; 13:1071215.
PMID: 36406990
Loss of fiber cell communication may contribute to the development of cataracts of many different etiologies.
Loss of fiber cell communication may contribute to the development of cataracts of many different etiologies. Front Physiol. 2022; 13:989524.
PMID: 36171977
Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice.
Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice. Cells. 2022 09 07; 11(18).
PMID: 36139360
Connexin Mutants Cause Cataracts Through Deposition of Apatite.
Connexin Mutants Cause Cataracts Through Deposition of Apatite. Front Cell Dev Biol. 2022; 10:951231.
PMID: 35938173
Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease.
Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease. J Clin Med. 2022 Feb 03; 11(3).
PMID: 35160266
Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation.
Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation. J Biol Chem. 2022 03; 298(3):101673.
PMID: 35120923
Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50?mutant.
Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50?mutant. Biophys J. 2021 12 21; 120(24):5644-5656.
PMID: 34762867
Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells".
Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells". Pediatr Res. 2021 03; 89(4):1036.
PMID: 33790407
Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome.
Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome. Int J Mol Sci. 2020 Nov 24; 21(23).
PMID: 33255173
Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens?
Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens? Biomolecules. 2020 10 07; 10(10).
PMID: 33036381
American Society for Clinical Investigation
Society for Pediatric Research
Fellow, American Heart Association
Fellow, Association for Research in Vision and Ophthalmology