People

Eric C. Beyer, MD PhD

  • Professor of Pediatrics
    Committee on Cancer Biology
    Committee on Molecular Medicine
  • Clinical Interests: Anemias, Blood Disorders, Childhood Cancers, Sickle Cell Disease
  • Research and Scholarly Interests: Arrhythmia, Cardiac, Cancer, Cataract, Cell Biology, Connexins, Endothelial Cells, Exosomes, Extracellular vessicles, Gap Junctions, Intercellular Junctions, Ion Channel, Lens, Eye, Sickle Cell Disease, Translational Medical Research
  • Websites: My Google Scholar site, Research Network Profile
  • Contact: ecbeyer@uchicago.edu
  • Graduate Program: Cancer Biology

Professor of Pediatrics

Section of Hematology/Oncology and Stem Cell Transplantation

University of Chicago
AB - Biological Sciences

UCSD
PHD - Physiology and Pharmacology

UCSD
MD - Medicine

Children's Hospital
Boston
Internship and Residency - Pediatrics

Children's Hospital and Dana Farber Cancer Center
Boston
Fellowship - Pediatric Hematology/Oncology

Editorial: Ion channels, pumps, and transporters in lens physiology and disease.
Editorial: Ion channels, pumps, and transporters in lens physiology and disease. Front Physiol. 2022; 13:1071215.
PMID: 36406990

Loss of fiber cell communication may contribute to the development of cataracts of many different etiologies.
Loss of fiber cell communication may contribute to the development of cataracts of many different etiologies. Front Physiol. 2022; 13:989524.
PMID: 36171977

Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice.
Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice. Cells. 2022 09 07; 11(18).
PMID: 36139360

Connexin Mutants Cause Cataracts Through Deposition of Apatite.
Connexin Mutants Cause Cataracts Through Deposition of Apatite. Front Cell Dev Biol. 2022; 10:951231.
PMID: 35938173

Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease.
Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease. J Clin Med. 2022 Feb 03; 11(3).
PMID: 35160266

Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation.
Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation. J Biol Chem. 2022 03; 298(3):101673.
PMID: 35120923

Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50?mutant.
Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50?mutant. Biophys J. 2021 12 21; 120(24):5644-5656.
PMID: 34762867

Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells".
Insights image for "Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells". Pediatr Res. 2021 03; 89(4):1036.
PMID: 33790407

Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome.
Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome. Int J Mol Sci. 2020 Nov 24; 21(23).
PMID: 33255173

Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens?
Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens? Biomolecules. 2020 10 07; 10(10).
PMID: 33036381

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American Society for Clinical Investigation

Society for Pediatric Research

Fellow, American Heart Association

Fellow, Association for Research in Vision and Ophthalmology

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